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In future, it is likely that the clinical indications for GLP- 1RAs will expand, with pharmaceutical companies running various drug trials to substantiate a wider array of use cases, such as the reduction of cardiovascular risk and the treatment of chronic kidney disease

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Yes, clinical trials have shown comparable results in glucose control and weight loss, depending on dose and adherence

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(2017) RIP1-dependent reactive oxygen species production executes artesunate induced cell death in renal carcinoma Caki cells, Mol